Chemosensitivity of cardiac muscle
نویسندگان
چکیده
منابع مشابه
Cardiac Muscle
1. Cardiac muscle is a striated muscle, with a sarcomere structure much like that of skeletal muscle. It has small cells (as in smooth muscle), firmly connected end-to-end at the intercalated disks. 2. The action potential in cardiac muscle is long lasting compared to the duration of the contraction, preventing a tetanic contraction. 3. Under normal circumstances, cardiac muscle operates at len...
متن کاملMetabolism of Cardiac Muscle
Both pyruvate and lactate are extracted by the intact myocardium at physiological levels (1, 2) and are rapidly burned to CO2 in the intact cardiac muscle slice. They are interconverted by the diphosphopyridine nucleotide-dependent lactic acid dehydrogenase system and share a common final pathway for terminal oxidation (3, 4). Since these substrates are so closely related in carbohydrate metabo...
متن کاملMechanochemistry of Cardiac Muscle
The aim of this study was to evaluate utilization of chemical energy in relation to myocardial mechanics in variably afterloaded contractions of cardiac muscle by determining total energy utilization (—P) in the absence of energy production. Right ventricular papillary muscles of cats were equilibrated at 26°C in a myograph in Krebs' solution while contracting isometrically (12/ min). Following...
متن کاملExcitation of Cardiac Muscle Cells
was used to deliver rectangular pulses for extracellular field stimulation of individual heart cells. We found that single frog and guinea pig ventricular myocytes are excitable with rectangular pulse field stimulation over a wide range of pulse durations, ranging from 10 msec to as little as 20 ,usec. The excitation field strength varies inversely with pulse duration as described by the Weiss-...
متن کاملRegulation of Cardiac Muscle Contractility
The heart's physiological performance, unlike that of skeletal muscle, is regulated primarily by variations in the contractile force developed by the individual myocardial fibers. In an attempt to identify the basis for the characteristic properties of myocardial contraction, the individual cardiac contractile proteins and their behavior in contractile models in vitro have been examined. The lo...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1967
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1967.sp008158